Cognitive Neuroscience of Memory Consolidation by Nikolai Axmacher, Björn Rasch

By Nikolai Axmacher, Björn Rasch

This edited quantity offers an outline the cutting-edge within the box of cognitive neuroscience of reminiscence consolidation. In a couple of sections, the editors acquire contributions of major researchers . The topical concentration lies on present problems with curiosity corresponding to reminiscence consolidation together with operating and long term reminiscence. specifically, the function of sleep relating to reminiscence consolidation should be addressed. the objective viewers basically contains learn specialists within the box of cognitive neuroscience however the e-book can also be necessary for graduate scholars.

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Extra resources for Cognitive Neuroscience of Memory Consolidation

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Later, functional neuroimaging studies of healthy young adults corroborated the conclusion that performance on these tests of mental navigation did not activate the hippocampus if the memory was acquired over a year ago and had become a familiar environment, but did activate the Mechanisms of Memory Consolidation and Transformation 27 hippocampus if the memory was more recent (Rosenbaum et al. 2005; Hirshhorn et al. 2012). Further investigation suggested that this preserved spatial ability relied on a schematized topographical representation, not unlike a skeletal cognitive map, that could be supported by extra-hippocampal representations.

S report (2002) of protein synthesis-dependent systems reconsolidation, over-expression of CREB in the hippocampus just prior to reactivation of a remote context memory enhanced reconsolidation of context-specific fear memory. This suggests that not only can a reminder bring a generalized remote memory back to a hippocampus-dependent, context-specific state, but the same molecular mechanisms underlying initial cellular consolidation also support systems consolidation and reconsolidation. e. synaptic remodeling) that support this facilitation of systems consolidation.

Behavioral studies have confirmed that perceptual, contextual, and central schematic elements that together make up human episodic memories decline at different rates over time, with perceptual and contextual details declining more rapidly (Thorndyke 1977; Bahrick 1984). As the hippocampus is critical for the representation of those perceptual and contextual details, our group used memory for film clips to determine how the network of brain activity changes as different elements of episodic memory are lost over time (Sekeres et al.

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