Biomateriomics by Steven W. Cranford, Markus J. Buehler (auth.)

By Steven W. Cranford, Markus J. Buehler (auth.)

Biomateriomics is the holistic examine of organic fabric structures. whereas such structures are definitely advanced, we often come across comparable parts -- common construction blocks and hierarchical constitution motifs -- which lead to a various set of functionalities. just like the way in which track or language arises from a constrained set of song notes and phrases, we make the most the relationships among shape and serve as in a significant method via spotting the similarities among Beethoven and bone, or Shakespeare and silk. in the course of the research of fabric homes, reading primary hyperlinks among strategies, constructions, and houses at a number of scales and their interactions, materiomics explains approach performance from the extent of establishing blocks.

Biomateriomics in particular focuses the research of the function of fabrics within the context of organic procedures, the move of organic fabric rules in the direction of biomimetic and bioinspired functions, and the examine of interfaces among dwelling and non-living platforms. The demanding situations of organic fabrics are gigantic, however the convergence of biology, arithmetic and engineering in addition to computational and experimental strategies have led to the toolset essential to describe advanced fabric structures, from nano to macro. using biomateriomics can release Nature’s mystery to excessive functionality fabrics akin to spider silk, bone, and nacre, and elucidate the development and analysis or the remedy of illnesses. equally, it contributes to strengthen a de novo figuring out of organic fabric tactics and to the potential for exploiting novel suggestions in innovation, fabric synthesis and design.

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Biomateriomics

Biomateriomics is the holistic examine of organic fabric platforms. whereas such platforms are definitely complicated, we regularly come across comparable elements -- common development blocks and hierarchical constitution motifs -- which lead to a various set of functionalities. just like the best way track or language arises from a constrained set of tune notes and phrases, we make the most the relationships among shape and serve as in a significant means by way of spotting the similarities among Beethoven and bone, or Shakespeare and silk.

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Extra resources for Biomateriomics

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Biomateriomics involves the rigorous understanding of the properties and mechanisms of biological matter. While this is an easy statement, integration of multiple disciplines is difficult in practice. Due to the rich history and unique perspectives of the fields that contribute to advances in fields contribution to materiomics, questions of interest, approaches, tools and even vocabulary particular to each community (the “disciplinary lexicon”, so-to-speak) can impede communication and progress in this inherently interdisciplinary venture.

Lim, S. Suresh, Mechanics of the human red blood cell deformed by optical tweezers. J. Mech. Phys. Solids 53(2), 493–494 (2005) 51. J. Buehler, S. Keten, T. Ackbarow, Theoretical and computational hierarchical nanomechanics of protein materials: deformation and fracture. Prog. Mater. Sci. 53, 1101–1241 (2008) 52. T. Akita, A. Ueda, Y. Yamada, S. Ichikawa, K. Tanaka, M. Kohyama, T. Kobayashi, Analytical tem observations of combinatorial catalyst libraries for hydrogen production—as a part of “materiomics”.

Transcriptomics RNA transcripts produced by the genome at any one time; transcriptome Examines the expression level of RNA in a given cell population, which vary with external environmental conditions, including mRNA, rRNA, tRNA, and non-coding RNA. Interactomics Interactions between all macromolecules in a cell; interactome Analyses and characterization of gene-gene, protein-protein, or protein-ligand interactions; development of molecular interaction maps/networks. Mechanomics Mechanical systems and processes within an organism; mechanome General role of force, stress transfer, mechanics, and molecular machinery in biology, encompassing biological motors, mechanical structures, and processes.

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