Biomaterials for spinal surgery by Luigi Ambrosio, Elizabeth Tanner

By Luigi Ambrosio, Elizabeth Tanner

There were vital advancements in fabrics and cures for the remedy of spinal stipulations. Biomaterials for spinal surgical procedure summarises this study and the way it really is being utilized for the good thing about sufferers. After an creation to the topic, half one experiences basic matters reminiscent of spinal stipulations and their pathologies, spinal a lot, modelling and osteobiologic brokers in spinal surgical procedure. half discusses using bone substitutes and synthetic intervertebral discs while half 3 covers issues reminiscent of using injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty in addition to scoliosis implants. the ultimate a part of the e-book summarises advancements in regenerative cures comparable to using stem cells for intervertebral disc regeneration.

Show description

Read or Download Biomaterials for spinal surgery PDF

Similar neurosurgery books

The human hippocampus: functional anatomy, vascularization, and serial sections with MRI

This publication deals an exact description of the anatomy of human hippocampus in view of neurosurgical development and the wealth of scientific imaging tools to be had. A survey of the present suggestions explains the capabilities of the hippocampus and describes its exterior and inner vascularisation. Head sections and magnetic resonance pictures entire this finished view of human hippocampal anatomy.

Essential Neurosurgery

Crucial Neurosurgery offers a entire creation to neurosurgery for junior surgical trainees and clinical scholars. The ebook concentrates at the rules of neurosurgical prognosis and administration of the extra universal important worried process difficulties, together with an realizing of neurology and the pathological foundation of neurological ailment.

NeuroPET: Positron Emission Tomography in Neuroscience and Clinical Neurology

Positron emission tomography (PET) presents independent in vivo dimension of neighborhood tracer task at very excessive sensitivity. this can be a exact estate unequalled through different imaging modalities. while PETwas brought into medication greater than 25years in the past, the 1st organ of significant curiosity was once the mind. because then, puppy has flourished as a really robust and flexible instrument in medical mind experiences, while its use as a diagnostic software in medical neurology is still restricted.

Biomaterials for spinal surgery

There were vital advancements in fabrics and cures for the remedy of spinal stipulations. Biomaterials for spinal surgical procedure summarises this examine and the way it truly is being utilized for the advantage of sufferers. After an creation to the topic, half one experiences primary concerns resembling spinal stipulations and their pathologies, spinal quite a bit, modelling and osteobiologic brokers in spinal surgical procedure.

Additional info for Biomaterials for spinal surgery

Sample text

Anderson, P. , Rouleau, J. , Bryan, V. E. and Carlson, C. S. (2003) ‘Wear analysis of the Bryan Cervical Disc prosthesis’, Spine, 28, S186–194. Athanasiou, K. , Shah, A. , Hernandez, R. J. and LeBaron, R. G. (2001) ‘Basic science of articular cartilage repair’, Clin Sports Med, 20, 223–247. , Jazrawi, L. , Kummer, F. J. and Spivak, J. M. (1999) ‘The use of an injectable, biodegradable calcium phosphate bone substitute for the prophylactic augmentation of osteoporotic vertebrae and the management of vertebral compression fractures’, Spine 24, 1521–1526.

They concluded that the PLA at 650 Da was best suited as a carrier for BMP due to its material properties, handling characteristics and resorbability. , 1999). Bone formation was less than expected, and the investigators felt it was due to the high acidity and rapid degradation of the low molecular weight homopolymer. A polyethylene glycol (PEG) moiety was added to the PLA homopolymer, and poly-d,l-lactic acid–polyethylene glycol (PLA-PEG) block copolymers were introduced. , 1993). , 2000). The excellent chemical resistance, physical properties and biodegradability of PVA have led to the development of many commercial products based on this polymer.

The ability to obtain such a wide range of tensile strength values makes the polymer appropriate for diverse applications. The dielectric behaviour of the polymer is determined by the charge distribution and also by statistical thermal motion of its polar group. Bao and Higham (1991, 1993) have approached nucleus replacement using physically crosslinked polyvinyl alcohol (PVA). The authors reported that PVA implant has similar mechanical properties to those of the nucleus as well as similar physiological properties, maintaining about 70% water content under physiological loading conditions.

Download PDF sample

Rated 4.83 of 5 – based on 13 votes