Atlas of CSF cytology by Harald Kluge

By Harald Kluge

A whole, single-volume reference for the cytological exam of
cerebrospinal fluid!

This full-color atlas provides all of the crucial
information wanted for attaining a correct cytological prognosis of
cerebrospinal fluid and its abnormalities. Designed as a medical and laboratory
reference, Atlas of CSF Cytology presents an summary of the entire average
diagnostic concepts and provides perception into complicated tools corresponding to circulate
cytometry and immunocytological phenotyping. short descriptions of the
indications, benefits, and barriers are supplied for every procedure. An
extensive number of greater than three hundred high quality cytological photographs
demonstrating basic mobilephone buildings, in addition to pathological cells in acute and
remission levels permits the reader to appreciate disorder processes.


  • Guidelines for the correct dealing with of specimens, phone training, and marking
  • Review of the typical resources of mistakes in prognosis
  • Thorough insurance of the options for detecting and classifying inflammatory,
    infectious, neoplastic, and hemorrhagic stipulations of the primary fearful process
  • Descriptions of the main beneficial properties of cells and the class of tumor
    cell forms in response to present W.H.O. criteria
  • Full-color pictures depicting pathological changes of CSF cells -- an critical visible reduction to

Atlas of CSF Cytology is perfect for experts in neurology,
neurosurgery, pathology/neuropathology, cytopathology, microbiology, and
laboratory drugs, in addition to for these internists, pediatricians, and
psychiatrists who often request cytological exam of the CSF. notwithstanding
it is written to satisfy the desires of experts, the "Atlas" may also be came upon
accessible and enlightening by way of scientific scholars, interns and

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Extra resources for Atlas of CSF cytology

Example text

A few of these are in the process of separating themselves from the cluster. Fig. 45 Polynuclear storage cell with peripherally located nuclei. Adjacent to it there are mononuclear progenitor cells (probably histiocytes) in an early stage of transformation. The erythrocyte (lower right) provides an indication of size. Fig. 46 A phagocytic polynuclear giant cell with a nearly even distribution of the nuclei in the cytoplasm which has a dispersed and finely granular appearance. Thieme-Verlag Frau Langner Sommer-Druck Feuchtwangen Kluge et al.

The cell picture contains activated monocytes and lymphocytes as well as many ghost cells. Artifactual admixture of blood is also seen. 33 Thieme-Verlag Frau Langner 34 Sommer-Druck Feuchtwangen Kluge et al. 2006 Chapter-3 3 Pathological CSF Cell Findings in Infectious and Inflammatory Diseases of the Central Nervous System Fig. 26 Relatively acute varicellazoster virus (VZV) meningitis with granulocytes and, most prominently, activated lymphocytes and plasma cells. Fig. 27 Subacute viral meningitis (pathogen unknown).

The activated monocytes or histiocytes are occasionally already engaged in erythro- and/or lipophagocytosis at this early stage (Figs. 9). This is most commonly seen in children in the early phase of hemorrhage into the CSF space. Erythrophages are the first type of hematomacrophage to develop from the activated cells of monocytic origin (see Figs. 11). They appear in the CSF about 8–12 hours after the precipitating hemorrhage (in the literature times range from 8 to 24 hours), rapidly increase in number in accordance with the extent and severity of the hemorrhage, and begin the task of the enzymatic breakdown of hemoglobin.

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