Andrology: Male Reproductive Health and Dysfunction by E. Nieschlag (auth.), Prof. Dr. med., FRCP Eberhard

By E. Nieschlag (auth.), Prof. Dr. med., FRCP Eberhard Nieschlag, Prof. Dr. med. Hermann M. Behre (eds.)

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Neurosci Biobehav Rev 17:427-439 Wickler W, Seibt U (1998) Männlich-Weiblich? Ein Naturgesetz und seine Folgen. Spektrum, Heidelberg Wilson HC (1992) A critical review of menstrual synchrony research. Psychoneuroendocrinology 17:565-591 World Bank (1984) World Development Report 11:113-138 CHAPTER 3 Physiology of Testicular Function G. F. WEINBAUER· 3 J. GROMOLL • M. SIMONI • E. 4. 7 References 57 The testis fulfills two essential functions: production and maturation of the male gametes and synthesis and secretion of the sexual hormones.

Defects during pubertal Sertoli cell differentiation can be associated with alterations of spermatogenesis in the adult testis (Steger et al. 1999a). In the rat, the experimental prolongation of the division phase of Sertoli cells, produced for example by a deprivation of thyroid hormones, results in an increase of testicular weight and sperm production by about 80 %. On the other hand, the decrease of Sertoli cell numbers such as that proauced by an antimitotic substance leads to a reduction of testicular volume and sperm production.

Proc Natl Acad Sei USA 95:6866-6869 Barteis I, Hansmann I, Eiben B (1990) Excess of females in chromosomally normal spontaneous abortuses. Am J Med Genet 35:297-298 Beamer WG, Whitten WK (1991) Do histocompatibility genes influence sex ratio (% males)? Reprod Fertil Dev 3:267-276 Booth BE, Verma M, Beri RS (1994) Fetal sex determination in infants in Punjab, India: correlations and implications. Br Med J 309:1259-1261 Chen SJ, Vohr BR, Oh W (1993) Effects of birth order, gender, and intrauterine growth retardation on the outcome of very low birth weight in twins.

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